PUBLICATIONS

Vous trouverez ci-dessous quelques publications de notre laboratoire; les liens électroniques sont fournis, le cas échéant.

• Dumas, A., Lagarde, S., Laflamme, C. and Pouliot, M.  (2011) Oncostatin M decreases interleukin-1 secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo.
  J. Mol. Cell. Med. Disponible en ligne avant publication. Lien Pubmed

• Dufresne, M., Dumas, G., Asselin, E., Carrier, C., Pouliot, M. and Reyes-Moreno, C. (2011) Pro-inflammatory type-1 and anti-inflammatory type-2 macrophages differentially modulate cell survival and invasion of human bladder carcinoma T24 cells.
  Mol. Immunol. 48 (12-13): 1556-1567. Lien Pubmed

• Allaeys, I., Rusu, D., Picard, S., Pouliot, M. Borgeat, P. and Poubelle, P.E. (2011) Osteoblast retraction induced by adherent neutrophils promotes osteoclast bone resorption: implication for altered bone remodeling in chronic gout.
  Lab. Invest.  91 (6): 905-920. Lien Pubmed

• Russell, F.A., Zhan, S., Dumas, A., Lagarde, S., Pouliot, M. and MacDougall, J.J. (2011) The pronociceptive effect of proteinase-4 stimulation in rat knee joints is dependent on mast call activation.
  PAIN 152 (2): 354-360. Lien Pubmed

• St-Onge, M. Lagarde, S., Laflamme, C., Rollet-Labelle, E., Marois, L., Naccache, P.H. and Pouliot, M. (2010) Proteinase-activated receptor-2 up-regulation by Fc gamma receptor activation in human neutrophils.
  FASEB J. 24 (6): 2116-2125. Lien Pubmed

• Dumas, A. and Pouliot, M. (2009) Le neutrophile: Ennemi ou ami?
  Med Sci (Paris). 25(8-9): 699-704. Lien Pubmed

• St-Onge, M., Dumas, A., Michaud, A., Laflamme, C., Dussault, A.-A. and Pouliot, M. (2009) Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: Unraveling endogenous resolution pathways.
  PLoS One 4 (3): e4902. Lien Pubmed

• Oh, D.-Y., Taube, S., Hamouda, O., Kücherer, C., Poggensee, G., Jessen, H., Eckert, J.K., Neumann, K., Storek, A., Pouliot, M., Borgeat, P., Oh, N., Schreier, E., Pruss, A., Hattermann, K. and Schumann, R.R. (2008) A Functional Toll-Like Receptor 8 Variant Is Associated with HIV Disease Restriction.
  J. Infect. Dis. 198 (5): 701-709. Lien Pubmed

• Leclerc, P., Biarc, J., St-Onge, M., Gilbert, C., Dussault, A.-A., Laflamme, C. and Pouliot, M. (2008) Nucleobindin co-localizes and associates with cyclooxygenase (COX)-2 in human neutrophils.
  PLoS One 3 (5): e2229. Lien Pubmed


• St-Onge, M., Flamand, N., Biarc, J., Picard, S., Bouchard, L., Dussault, A.-A., Laflamme, C., James, M.J., Caughey, G.E., Cleland, L.G., Borgeat, P. and Pouliot, M. (2007) Characterization of prostaglandin E₂ generation through the cyclooxygenase (COX)-2 pathway in human neutrophils.
  Biochim. Biophys. Acta. 1771 (9): 1235-1245. Lien Pubmed


• St-Onge, M. and Pouliot, M. (2007) Neutrophils and pain: Dialogue with the nervous system. Dans: Phenotypic and Functional changes of neutrophils activated by recently identified modulators (Girard, D. Ed.). Research SignPost.


• Hattermann, K., Picard, S., Borgeat, M., Leclerc, P., Pouliot, M. and Borgeat, P. (2007) The toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B₄, prostaglandin E₂ and platelet-activating factor biosynthesis.
  FASEB J. 21 (7): 1575-1585. Lien Pubmed
  


• Flamand, N., Picard, S., Lemieux, L., Pouliot, M., Bourgoin, S.G. and Borgeat, P. (2006) Effects of pyrrophenone, an inhibitor of group IVA phospholipase A₂, on eicosanoid and PAF biosynthesis in human neutrophils.
  Br. J. Pharmacol. 149 (4): 385-392. Lien Pubmed
  
  
• Pouliot, M. (2006) Adenosine and neutrophil functions. Dans: Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases (Hasko, G. Cronstein, B. & Szabo, C. Eds.). CRC Taylor & Francis. pp 89-100.
  
  
• McDougall, J., Backman, C, Fiddler, J., Gignac, M., Henry, J., Li, L. and Pouliot, M. (2006) Workshop on Pain and Arthritis, Calgary, Alberta, Canada, 28-29 janvier. Lien PDF


• Dussault, A.A. and Pouliot, M. (2006) Rapid and simple comparison of messenger RNA levels using real-time PCR.
  Biol. Proced. Online 8 (1): 1-10. Lien Pubmed
  
  
• McColl, S.R., St-Onge, M., Dussault, A.A., Laflamme, C., Bouchard, L., Boulanger, J. and Pouliot, M. (2006) Immunomodulatory impact of the A_2A adenosine receptor on the profile of chemokines produced by neutrophils.
  FASEB J. 20 (1): 187-189. Lien Pubmed
  
  
• O'reilly, S.M., Leonard, M.O., Kieran, N., Comerford, K.M., Cummins, E., Pouliot, M., Lee, S.B. and Taylor, C.T. (2006) Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner.
  Am J. Physiol. Cell Physiol. 290 (2): C592-C600. Lien Pubmed
  
  
• Cadieux, J.-S., Leclerc, P., St-Onge, M., Dussault, A.-A., Laflamme, C., Picard, S., Borgeat, P. and Pouliot, M. (2005) Potentiation of Neutrophil Cyclooxygenase-2 Expression by Activation of the Adenosine A_2A Receptor: A Pivotal Anti-Inflammatory Signal.
  J. Cell Sci. 118 (7): 1437-1447. Lien Pubmed
  
  
• Pouliot, M. (2004) The causes of chronic disease: A new theory implicates viruses. Critique du livre: Microcompetition with foreign DNA and the origin of chronic disease. Hanan Polansky. (CBCD, Rochester, NY 1^st Ed. 2003)
  Cell cycle 3 (4) : 519-520.
  
  
• Fiset, M.-É., Gilbert, C., Poubelle, P.E. and Pouliot, M. (2003) Human neutrophils as a source of nociceptin: A novel link between pain and inflammation.
  Biochemistry 42 (35): 10498-10505. Lien Pubmed
  
  
• Gilbert, C., Poubelle, P. E., Borgeat, P., Pouliot, M. and Naccache, P. H. (2003) Crystal-induced neutrophil activation. VIII. Rapid production of prostaglandin E₂ by human neutrophils in the presence of monosodium urate monohydrate crystals.
  Arthritis Rheum. 48 (4): 1137-1148. Lien Pubmed
  
  
• Pouliot, M., Fiset, M.-É., Massé, M., Naccache, P. H. and Borgeat, P. (2002) Adenosine up-regulates cyclooxygenase-2 in human granulocytes: Impact on the balance of eicosanoid generation.
  J. Immunol. 169 (9): 5279-5286. Lien Pubmed
  
  
• Serhan, C. N., Fierro, I. M., Chiang, N. and Pouliot, M. (2001) Nociceptin stimulates neutrophil chemotaxis and recruitment: Inhibition by aspirin-triggered-15-epi-lipoxin A₄.
  J. Immunol., Cutting Edge 166 (6): 3650-3654. Lien Pubmed
  
  
• Pouliot, M., Clish, C. B., Petasis, N. A., Van Dyke, T. E. and Serhan C. N. (2000) Lipoxin A₄ analogs inhibit leukocyte recruitment to porphyromonas gingivalis: A role for cyclooxygenase-2 and lipoxins in periodontal disease.
  Biochemistry 39 (16): 4761-4768. Lien Pubmed
  
  
• Hachicha, M., Pouliot, M., Petasis, N. A. and Serhan, C. N. (1999) Lipoxin A₄ and aspirin-triggered 15-epi-LXA₄ inhibit TNFalpha-initiated neutrophil responses and trafficking: Regulators of a cytokine-chemokine axis.
  J. Exp. Med. 189 (12): 1923-1929. Lien Pubmed
  
  
• Pouliot, M., Serhan, C. N. (1999) Lipoxin A4 and aspirin-triggered 15-epi-LXA₄ inhibit TNFalpha-initiated neutrophil responses and trafficking: novel regulators of a cytokine-chemokine axis.
  J. Periodontal Res. 34 (7): 370-373. Lien Pubmed
  
  
• Pouliot, M., Gilbert, C., Borgeat, P., Poubelle, P. E., Bourgoin, S.G., Créminon, C., Maclouf, J., McColl, S. R. and Naccache, P. H. (1998) Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils.
  FASEB J. 12 (12): 1109-1123. Lien Pubmed
  
  
• Borgeat, P., Picard, S., Dallaire, N., Pouliot, M. and Surette, M. (1998) Quantitative studies of the lipid mediators of inflammation using liquid chromatography-electrospray mass spectrometry. Dans: Molecular and cellular basis of inflammation (Eds C.N. Serhan & P.A. Ward), Humana Press Inc. Totowa, New Jersey. pp 275-288.
  
  
• Pouliot, M., James, M. J., McColl, S. R., Naccache, P. H. and Cleland, L. G. (1998) Monosodium urate microcrystals induce prostaglandin G/H synthase-2 (COX-2) in human monocytes.
  Blood 91 (5): 1769-1776. Lien Pubmed
  
  
• Pouliot, M., Baillargeon, J., Lee, J. C., Cleland, L. G. and James, M. J. (1997) Inhibition of prostaglandin endoperoxide synthase-2 expression in stimulated human monocytes by inhibitors of p38 mitogen-activated protein kinase.
  J. Immunol. 158 (10): 4930-4937. Lien Pubmed
  
  
• Caughey, G. E., Pouliot, M., Cleland, L. G. and James, M. J. (1997) Regulation of tumor necrosis factor alpha and interleukin-1 beta by thromboxane A₂ in human monocytes.
  J. Immunol. 158 (1): 351-358. Lien Pubmed
  
  
• Borgeat, P., Krump, E., Palmantier, R., Picard, S., Dallaire, N., McDonald, P. P., Pouliot, M., Surette, M. E. and McColl, S. R. (1997) The synthesis of leukotrienes by the human neutrophil. Dans: From SRS-A to leukotrienes (Eds S. Holgate and S.E. Dahlén), Blackwell Sciences. pp 69-84.
  
  
• Pouliot, M., Mcdonald, P. P., Krump, E., Mancini, J. A., McColl, S. R., Weech, P. K. and Borgeat, P. (1996) Co-localization of cytosolic phospholipase A₂, 5-lipoxygenase, and 5 lipoxygenase-activating protein at the nuclear membrane of A23187-stimulated human neutrophils.
  Eur. J. Biochem. 238 (1): 250-258. Lien Pubmed
  
  
• Krump, E., Pouliot, M., Naccache, P. H. and Borgeat, P. (1995) Leukotriene synthesis in calcium-depleted human neutrophils: Arachidonic acid release correlates with calcium influx.
  Biochem. J. 310: 681-688. Lien Pubmed
  
  
• Pouliot, M., McDonald, P. P., Borgeat, P. and McColl, S. R. (1994) Stimulation of the 5 lipoxygenase-activating-protein (FLAP) expression by granulocyte-macrophage colony-stimulating factor and dexamethasone in human neutrophils.
  J. Exp. Med. 179 (4): 1225-1232. Lien Pubmed
  
  
• Pouliot, M., McDonald, P. P., Khamzina, L., Borgeat, P. and McColl, S. R. (1994) Recombinant human granulocyte-macrophage colony-stimulating factor enhances 5 lipoxygenase expression in human polymorphonuclear leukocytes.
  J. Immunol. 152 (2): 851-858. Lien Pubmed
  
  
• McDonald, P. P., Pouliot, M., Borgeat, P. and McColl, S. R. (1993) Induction by chemokines of lipid mediator synthesis in granulocyte-macrophage colony-stimulating factor-treated human neutrophils.
  J. Immunol. 151 (11): 6399-6409. Lien Pubmed
  
  
• McDonald, P. P., Pouliot, M., and Borgeat, P. (1993) Enhancement by GM-CSF of agonist-induced 5-lipoxygenase activity in human neutrophils: Involvement of protein synthesis and gene transcription.
  J. Lipid Mediat Cell. 6 (1): 59-67. Lien Pubmed
  
  
• Chafouleas, J. G. and Pouliot, M. (1987) Potentiation of bleomycin lethality and inhibition of DNA repair by anti-calmodulin drugs is associated with the selective inhibition of expression of a 55 kDa calmodulin-binding-protein. Dans: Proceedings of the 5th International Symposium on calcium binding proteins in health and disease (Eds A.W. Norman et al.), Academic Press, New-York. pp 618-620.